Hub & Guide

The same framework, without the consultation.

Not everyone needs, or can get to, a Mayfair consulting room. The Hub is open to patients and practitioners; the Clinician's Guide is written for healthcare professionals. Both are built on exactly what I use in clinic.

The Methylation Hub: free and premium education community on methylation and genetics, showing the methionine cycle (methionine, SAMe, SAH, homocysteine)

Community

The Methylation Hub

A community for people working through MTHFR and methylation issues, organised around the same five-stage sequence I use with patients.

Free tier includes

The full Foundations archive · the fertility and methylation course · the community itself

Membership adds

Live Q&A and recordings · The MTHFR Clinician's Guide free on the annual plan · $29 monthly or $290 annually

Join the Hub on Skool
The MTHFR Clinician's Guide by Dr Jean-Marc Sobczyk, MD: hardcover book and tablet edition

Guide

The MTHFR Clinician's Guide

Written for clinicians. A 64-page clinical walkthrough of the sequence I use in practice: which markers to run, how to interpret what comes back, and the order in which to act on it.

Covers

Which markers are worth running · interpreting homocysteine, active B12, RBC folate and RBC magnesium · the cofactor groundwork · how to introduce donors without the crash

Price

$59 standalone, or free with annual Hub membership

Get the Clinician's Guide

The Clinician's Guide is written for registered healthcare professionals. It supports, and does not replace, individual clinical judgement and current UK guidance.