A couple holding hands on a wooden rail, in black and white (posed by models)

Fertility · Evidence review

MTHFR and recurrent miscarriage: what the evidence shows

What MTHFR does, why the guidelines advise against routine testing and blood thinners for MTHFR alone, why homocysteine matters more than the gene, and how to prepare for your next pregnancy.

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Smiling woman in sunglasses making peace signs, illustrating renewed energy (posed by a model)

Methylation · Clinical case

Methyl B12 intolerance: three mechanisms and the hydroxocobalamin switch

Why some patients feel worse on methylcobalamin: overmethylation, methyl trapping or oxidative stalling of methionine synthase, and why changing one molecule can unlock a stuck protocol.

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A woman eating a balanced meal of salad, broccoli and vegetables (posed by a model)

Fertility · Guide

PCOS and fertility: your complete guide

How PCOS affects fertility for both partners, the role of insulin resistance, five practical changes to make this week, and when to seek professional help.

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Clinician's hand gently examining the front of a woman's neck where the thyroid gland sits (posed by models)

Fertility · Guide

Thyroid health and fertility: a guide to optimising conception

How thyroid function affects fertility in women and men, which tests to ask for, five practical changes to make this week, and when to seek help.

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A smiling couple cooking a fresh meal with leafy greens and lemons (posed by models)

Fertility · Guide

Blood sugar and fertility: your guide to conception success

How blood sugar and insulin resistance affect fertility for both partners, a 7-day plan of five practical changes, and when to seek professional help.

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